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Bruce K. Micales, M.S.

 

Education:  
Delaware Valley College Of Science and Agriculture B.S. Biology  
VPI and State University M.S. Specialization: Microbiology  
Work Experience:
1979 - 1980 Laboratory Specialist Biology Dept., VPI and SU, Blacksburg, VA  
1980 – 1984 Graduate Student Teaching Assistant, Biology Dept., VPI and SU, Blacksburg, VA  
1984 - 1985  Research Technician, Dept. of Radiation Medicine, Georgetown University Hospital Georgetown, Washington D. C.  
1985 - 1988 Research Specialist,  Dept. of Food Microbiology and Toxicology, University of Wisconsin, Madison, WI.  
1988 - 1989 Research Specialist,  Dept. of Medical Microbiology and Immunology, University of Wisconsin, Madison, WI
1990 - 1992 Research Specialist,   Dept. of Biomolecular Chemistry, University of Wisconsin, Madison, WI 
1992 to present Research Specialist, Dept. of Anatomy, University of Wisconsin, Madison, WI. 
Publications in Dr. Lyons' lab:  
1. Brandt, C.R., A.M. Pumfrey, B.K. Micales, C.D. Bindley, G.E. Lyons, S.J. Sramek, and I.H.L. Wallow. (1994) Renin mRNA is synthesized locally in   rat ocular tissues.  Curr. Eye Res. 13: 755-763.
2. Lyons,G.E., Micales, B. K., Herr, M. , Namciu, S. , Shaudy, D. , and Stavnezer., E.  (1994) The protooncogene, c-ski, is expressed in both proliferating and postmitotic neuronal populations..  Dev. Dynamics: 201: 354-365.
3. Lyons, G.E., B.K. Micales, J. Schwarz, J.F. Martin, and E.N. Olson. (1995). Expression of mef2  genes in the mouse central nervous system suggests a role in neuronal maturation.  J. Neurosci. 15:5727-5738.  
4. Lyons, G.E., Namciu, S.,  Micales, B., Heyman, H.C.., Horrigan, S., Colmenares, C. and Stavnezer, E. (1995) Enhanced expression of mouse c-ski  accompanies terminal sketetal muscle differentiation in vivo and in vitro. Dev. Dynamics 204: 291-300  
5. Edwards, J.G., Lyons, G. E., Micales, B. K., Malhotra, A., Factor, S.. and Leinwald, L.A.  (1996) Cardiomyopathy in transgenic myf5 mice.  Circ. Res. 78:379-387.  
6. Lyons, G.E., Micales, B.K., Kim, S., Herr, M. and Swanson, B.J. (1996) In situ analysis of muscle gene expression in mouse embryos. J. Animal Sci. 74 (Suppl. 2):1-8.  
7. Baker, R.K., Haendel, M.A., Swanson, B.J., Shambaugh, J.C., Micales, B.K. and Lyons, G.E. (1997) In vitro preselection of gene-trapped embryonic stem cell clones for characterizing novel developmentally regulated genes in the mouse. Dev. Biol. 185:201-214.  
8. Rai, S.K., Micales, B.K., Wu, M.S., Cheung, D.S., Pugh, T.D., Lyons, G.E. and Salvato, M.A. (1997) Timed appearance of lymphocytic choriomeningitis virus after gastric inoculation of mice.  Am. J. Pathol. 151: 633-639.  
9. Ferhat, L., Kuriyama, R., Lyons, G.E., Micales, B. and Baas, P.W. (1998) Expression of the mitotic motor protein CHO1/MKLP1 in postmitotic neurons. European J. Neurosci.. 10:1383-1393.  
10. Lee, Y., Baker, R.K., Song, A., Micales, B.K., Conway, S. and Lyons, G.E. (2000) Jumonji, a nuclear protein that is necessary for normal heart development. Circ. Res. 86:932-938.
11. Barlow, G.M., Micales, B., Lyons, G.E. and Korenberg, J.R. (2001) Down Syndrome Cell Adhesion Molecule is conserved in mouse and highly expressed in adult mouse brain. Cytogenetics and Cell Genetics. 94:155-162
12. Barlow, G.M., Micales, B., Chen, X-N., Lyons, G.E., and Korenberg, J.R. (2002) Mammalian DSCAMs: roles in the development of the spinal cord, cortex and cerebellum? Bioch Biophys Res Comm, 293:881-91.
13.. Micales, B.K. and Lyons, G.E. (2001) In Situ Hybridization: Use of 35S-Labeled Probes on Paraffin Tissue Section. METHODS, 23:313-323  
14. Lyons G.E., R. Baker, L. Bauer, A. Griffin, H. Hwang, C. Berrios, J. Grilley, A. Petrie, G. Chiang and B. Micales (2002) Insertional mutation of Rnf4 is recessive lethal and causes congenital heart defects in null mice. Submitted for publication.

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