GB

Gerard Bittner, B.S

Education:
University of Wisconsin-Madison	B.S.	Medical Technology
University of Wisconsin Center-Baraboo	1973-1974	Nuclear Engineering
University of Wisconsin-LaCrosse	1971-1972	Math

Work Experience:
2000-present	Self employed
1987-2000	Research Assistant (Dr. Joan H. Schiller, M.D.), Depart. of Human Oncology, William S. Middleton VA Memorial Hospital, Madison, WI.
1982-1987	Research Assistant (Dr. James Willson, M.D.), Depart. of Human Oncology, William S. Middleton VA Memorial Hospital, Madison, WI.
1980-1982	Assistant Research Scientist, Depart. of Genetics, Southwest Foundation for Research and Education, San Antonio, TX.
1979-1980	Research Specialist, Depart. of Genetics, University of Wisconsin-Madison, Madison, WI.
1977-1979	Laboratory Assistant. Depart. of Physiological Chemistry, University of Wisconsin-Madison, Madison, WI.

Awards and Honors
1969	High School Math Talent Search
1971	High School Math Talent Search

Publications:

1.	Schiller JH, Bittner G. (1999) Potentiation of platinum antitumor effects in human lung tumor xenografts by the angiogenesis inhibitor squalamine: effects on tumor neovascularization. Clin Cancer Res. 5:4287-4294.
2.	Schiller JH, Bittner G, Wu SQ, Meisner L. (1998) Karyotypic changes associated with spontaneous acquisition and loss of tumorigenicity in a human transformed bronchial epithelial cell line: evidence for in vitro selection of transformed clones. In Vitro Cell Dev Biol Anim. 34:283-289.
3.	Wittenkeller JL, Storer B, Bittner G, Schiller JH. (1997) Comparison of spontaneous and induced mutation rates in an immortalized human bronchial epithelial cell line and its tumorigenic derivative. Oncology. 54:335-341.
4.	Schiller JH, Bittner G. (1995) Loss of the tumorigenic phenotype with in vitro, but not in vivo, passaging of a novel series of human bronchialepithelial cell lines: possible role of an alpha 5/beta 1-integrin-fibronectin interaction. Cancer Res. 55:6215-6221.
5	Schiller JH, Sabatini L, Bittner G, Pinkerman CL, Mayotte J, Levitt M, Meisner L. (1994) Phenotypic, molecular and genetic characterization of transformed human bronchial epithelial cell strains. International Journal of Oncology 4:461-470
6.	Arbaje YM, Bittner G, Yingling JM, Storer B, Schiller JH. (1993) Antiproliferative effects of interferons-a and -b in combination with 5-fluorouracil, cisplatin, and cis- and trans-retinoic acid in three human lung carcinoma cell lines. J Interferon Res. 13:25-32.
7.	Schiller JH, Bittner G, Spriggs DR. (1992) Tumor necrosis factor, but not other hematopoietic growth factors, prolongs the survival of hairy cell leukemia cells. Leuk Res. 16:337-346.
8.	Schiller JH, Bittner G, Meisner LF, Oberley TD, Norback D, Schwabe M, Faltynek CR, Raab-Traub N. (1991) Establishment and characterization of an Epstein-Barr virus spontaneously transformed lymphocytic cell line derived from a hairy cell leukemia patient. Leukemia. 5:399-407.
9.	Schiller JH, Bittner G. (1990) Anti-proliferative effects of tumor necrosis factor, gamma interferon and 5-fluorouracil on human colorectal carcinoma cell lines. International Journal of Cancer 46:61-66.
10.	Schiller JH, Horisberger MA, Bittner G, Carlin JM, Storer B, Byrne GI, Willson JK, Borden EC. (1990) Effects of combinations of interferon-b_ser and interferon-g on interferon-inducible proteins and on the cell cycle. J Biol Response Mod. 9:368-377.
11.	Schiller JH, Bittner G. (1990) Anti-proliferative effects of tumor necrosis factor, gamma interferon and 5-fluorouracil on human colorectal carcinoma cell lines. Int J Cancer. 46:61-66.
12.	Schiller JH, Storer B, Bittner G, Horisberger MA. (1990) Characterization of the synergistic antiproliferative effects of interferon-gamma and tumor necrosis factor on human colon carcinoma cell lines. J Interferon Res. 10:129-139.
13.	Schiller JH, Storer B, Bittner G, Willson JK, Borden EC. (1988) Phase II trial of a combination of interferon-b_ser and interferon-gamma in patients with advanced malignant melanoma. J Interferon Res. 8:581-589.
14.	Willson JKV, Weese JL, Bittner G, Meisner LF. (1987) The development of techniques that permit the selection and growth of malignant cells from human colonic carcinomas: In: Cell Separation: Methods and Selected Applications, TG Pretlow and TP Pretlow (eds), Academic Press, 1987.
15.	Schiller JH, Bittner GN, Storer B, Willson JKV. (1987) Synergistic antitumor effects of tumor necrosis factor and gamma interferon in human colon carcinoma cell lines. Cancer Research 47:2809-2813.
16.	Willson JKV, Bittner G, Oberley TD, Meisner L, Weese JL. (1987) Human colon neoplastic cells in culture. Cancer Research 47:2704-2713.
17.	Schiller JH, Willson JKV, Bittner G, Wolberg WH, Hawkins MJ, Borden EC. (1986) Antiproliferative effects of interferons on human melanoma cells in the human tumor colony forming assay. Journal of Interferon Research 6:615-625.
18.	Fischer PH, Pamukcu R, Bittner G, Willson JKV. (1984) Enhancement of the sensitivity of human colon cancer cells to growth inhibition by acivicin achieved through inhibition of nucleic acid precursor salvage by dipyridamole. Cancer Research 44:3355-3359.
19.	Willson JKV, Bittner G, Borden EC. (1984) Antiproliferative activity of human interferons against ovarian cancer cells grown in human tumor stem cell assay. Journal of Interferon Research 4:441-447.
20.	VandeBerg JL, Bittner GN, Benforado K, Curie-Cohen M, Stone WH. (1982) Biochemical genetics of macaques. III. Inheritance of carbonic anhydrase II polymorphism in rhesus monkeys. Biochemical Genetics 20(5/6).
21..	VandeBerg JL, Bittner GN, Meyer GS, Kunz HW, Gill TJ III. (1980) Linkage of neuraminidase and a-mannosidase to the major histocompatibility complex in the rat. Journal of Immunogenetics 8:239-242.